ALCAT Methodology

The ALCAT Test:

The ALCAT Test differs from other food allergy or intolerance tests as it accurately and objectively measures leukocyte cellular reactivity in whole blood, which is a final common pathway of all mechanisms. The test utilizes electronic, state of the art, hematological instrumentation. Standard allergy tests, such as skin testing or RAST are not accurate for delayed type reactions to foods and chemicals. They measure only a single mechanism, such as the effect of mast cell release of histamine or the presence of allergen specific IgE molecules. Delayed reactions to foods and chemicals are NOT IgE mediated.

The ALCAT Test also differs from standard IgG tests in that they rely exclusively on one immune pathway, serum levels of immunoglobulin G (IgG). In fact, high food specific IgG titers are indicative only of exposure, not necessarily intolerance.

The ALCAT Test reproducibly measures the final common pathway of all pathogenic mechanism; whether immune, non-immune, or toxic. It is the only test shown to correlate with clinical symptoms by double blind oral challenges, the gold standard.

Technology:

ROBOCAT II

The ROBOCat II instrument is an automated liquid handling system
designed to measure blood cells using the electronic principle of
particle counting and sizing (measuring changes in electrical
resistance produced by a blood cell suspended in a conductive
liquid traversing a small aperture). The unit consists of an XYZ robotic
sample processor (belt driven, stepper motor controlled on X and Y
axises and air driven Z axis), air driven modular syringe pump with 3-
port distribution valve, vacuum/pressure pump, solenoid valves for
ow control, 12 and 24 VDC linear power supplies, aperture Plate
(reading area) and a main controller board that communicates with
the front-end PC via the RS232 port. All components are modular
thus allowing easy access for troubleshooting and replacement. The
software is compatible with all versions of Microsoft Windows. The
instrument is manufactured using Good Manufacturing Practices in a
FDA Registered Medical Device Establishment (facility registration
number: 1051901).

• State of the art food and chemical sensitivity testing - The ALCAT Test
• CE Marked for the European Union
• TÜV Certified and safety monitored
• Supported by the EU and the State of Brandenberg

Studies/Editorials:

Clinical Studies

Editorial Articles

Case Studies